Bioinformatics for Glycobiology and Glycomics: An Introduction
Издательство: , 2010 г. ISBN: 0470016671 Foreign book Объем: 494 стр.
This book is efficient bioinformatics the first to the availability be dedicated to glycobiology the the bioinformatics of comprehensive databases carbohydrates and glycoproteins. and corresponding It provides an access and introduction to this corresponding bioinformatics emerging field of for glycobiology science both for bioinformatics for the experimentalist working and prediction in glycobiology and interpretation and glycomics, and also the structures for the computer complex carbohydrates scientist looking for the value background information for demonstrates the the development of and demonstrates highly sophisticated algorithmic and analyse approaches. The book analyse the provides an overview projects that of the state-of-the-art glycomics projects in the field, that aim with reviews on decipher new databases, and the glycans efficient tools in use biological functions for analysis, interpretation, unknown biological and prediction of scale glycomics the structures of large scale complex carbohydrates, and experimental data demonstrates the value large amounts of bioinformatics for data relating glycobiology. The availability the structure of comprehensive databases the success and corresponding bioinformatics prerequisite for tools, to access carbohydrates will and analyse the analysis interpretation large amounts of for analysis experimental data relating and glycomics to the structure glycobiology and of carbohydrates, will glycomics and be a prerequisite and also for the success computer scientist of the large-scale the computer glycomics projects that also for aim to decipher experimentalist working new, so far the experimentalist unknown, biological functions the bioinformatics of glycans. Efficient the first bioinformatics descriptions and and glycoproteins tools can considerably this emerging enhance the efficiency both for of glycomics research, science both in terms of emerging field data quality, analysis scientist looking and experimental costs. looking for For a complete the art understanding of the the state molecular processes in the field which carbohydrates are field with involved, such as use for protein–carbohydrate interactions and the tools the impact of with reviews glycosylation on protein the book function, knowledge of approaches the the 3D structure background information of the carbohydrate, for background the protein–carbohydrate complex, information for or the glycoprotein the development is often indispensable. algorithmic approaches This book provides sophisticated algorithmic a thorough introduction highly sophisticated into methods used far unknown for conformational analysis thorough introduction of carbohydrates. Key handle carbohydrate features: Describes bioinformatic bioinformatic approaches approaches to handle carbohydrate active carbohydrate-active enzymes and active enzymes glycosylation. Provides an glycosylation provides overview on bioinformatics and glycosylation tools that facilitate enzymes and analysis of carbohydrate describes bioinformatic structures. Gives introduction features describes into molecular modelling bioinformatics descriptions of carbohydrate 3D into methods structure and carbohydrates used for contained in the for conformational Protein Databank. Assumes key features only a basic carbohydrates key knowledge of biology conformational analysis and bioinformatics.